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2006 Mar-Apr;26(2B):1433-7

"Most of it's from animal research." Concerns about cancer and other side effects One of Ghen's biggest concerns involves peptides that may increase VEGF, or vascular endothelial growth factor, a protein that helps form blood vessels

Medical interventions may also be appropriate: Discuss antacid therapy with your GP : If reflux appears to be contributing, medications such as proton pump inhibitors (e.g., omeprazole) or H2-receptor antagonists (e.g., famotidine) may help, though these should only be used under medical supervision